Nikki Hubers

The paper develops a polygenic score for dizygotic twinning, showing it explains 1.6% of liability variance and is linked to fertility outcomes and genetic correlations with related conditions.

This study identifies 21 infertility loci and over 400 reproductive hormone loci through GWAS across multiple cohorts, finding limited genetic correlation between reproductive hormones and infertility.

The paper compares transcriptomic and metabolomic data from monozygotic and dizygotic twins to identify molecular biomarkers of twinning, finding no replicable transcript-level differences but highlighting potential pathways.

This paper introduces FLAMES, a framework that improves gene prioritization in GWAS loci by integrating SNP-based and convergence-based evidence, outperforming single-modality approaches.

This study integrates genomics, epigenomics, and metabolomics data to identify ADHD biomarkers and explore omics-level connections, finding associations between PGSs, CpGs, and metabolites.

This study identifies proteins and genes associated with BMI and its changes in twins, showing shared genetic and environmental factors across proteome, transcriptome, and metabolome layers.