Mak A. Saito

This study uses proteomics to show that Pseudomonas aeruginosa adjusts its cobalamin homeostasis and pathogenicity in response to temperature changes, revealing temperature-dependent shifts in metabolic strategies.

The paper investigates how genomic diversity influences nutrient stress plasticity in Synechococcus through pan-proteome regulation, showing that strain-specific proteomic adjustments enhance elemental plasticity.

This study examines how zinc and carbonate chemistry affect the carbon concentrating mechanism and growth of the diatom P. tricornutum.

The paper studies bacterial iron acquisition under low carbon conditions and finds that amino acids facilitate iron uptake by E. coli.

This study shows that ammonia oxidizers contribute only a small fraction to dark ocean DIC fixation, challenging the assumption that nitrification primarily sustains carbon fixation in the deep ocean.

This study identifies temporal regulation of metabolic processes in Crocosphaera watsonii WH8501 using proteomics, revealing coordinated protein abundance patterns across diel cycles.

This study characterizes the microbiomes of Phaeocystis antarctica colonies in the Southern Ocean and laboratory culture, showing shifts in bacterial composition and highlighting the importance of field studies for understanding microbial interactions.

This study uses 2D metalloproteomics to analyze iron distribution in Pseudomonas aeruginosa under oxic and anoxic conditions, revealing distinct iron-associated protein complexes and their functional roles.

This study uses mass spectrometry to analyze proteomic changes in Pseudomonas aeruginosa under varying zinc availability, revealing insights into zinc homeostasis mechanisms.

This study compares DIA-MS and DDA-MS for metaproteomics, finding DIA-MS provides more reproducible and accurate protein and peptide identifications across laboratories.

The paper examines iron acquisition and cycling in the North Pacific subtropical gyre by analyzing siderophore production and utilization across depth and time.

The paper identifies a consistent specialized metabolome in Trichodesmium thiebautii blooms and isolates a new macrocyclic compound, suggesting potential ecological roles for these metabolites.

The paper uses metatranscriptomic and metaproteomic analysis of plankton biomass collected across a 1,050 km transect in the western North Atlantic Ocean to reveal shifts in microeukaryote community composition and metabolic function across depth and environmental gradients.

METATRYP v2 identifies shared peptides across organisms in metaproteomics to improve taxonomic attribution, showing low peptide sharing among marine microbes and coronaviruses.

The paper develops the Ocean Protein Portal (OPP) to address big-data challenges in marine microbial proteomics by enabling data sharing, discovery, and educational use through interactive visualizations and metadata links.