Area under the curve quantification outperforms spectral counting in metaproteomics, but matching between runs is detrimental
Ayesha Awan, J. Alfredo Blakeley‐Ruiz, Manuel Kleiner, Tjorven Hinzke
The paper compares AUC and SpC quantification methods in metaproteomics, finding AUC outperforms SpC in accuracy and dynamic range, but MBR harms AUC results.