Yee Lian Chew

The paper identifies cathepsin B (CPR-4) as a regulator of synaptic remodelling during learning in C. elegans using synaptic proteomics.

This paper shows that ALS/FTD-linked TDP-43 mutations cause DNA breaks in genes controlling excitatory neurotransmission by impairing topoisomerase IIβ function.

This study investigates dopamine's role in forgetting in C. elegans, showing that dopamine-deficient mutants have enhanced learning and that DOP-2 and DOP-3 receptors modulate forgetting.

This study uses proximity labelling in C. elegans to identify proteins involved in appetitive gustatory learning, revealing novel regulators and pathways.

This paper introduces a flow cytometry-based method to quantify protein inclusions in C. elegans, demonstrating its applicability across multiple aggregation models and its ability to monitor inclusion dynamics under stress and aging.

This study identifies a sex-specific role of the lury-1 neuropeptide in feeding and mating behaviors of male C. elegans.

The paper develops methods to analyze sleep and neural activity in adult C. elegans, finding that sleep increases arousal threshold without altering sensory neuron responses.