Author

Lavanya Saxena

Rice UniversityORCID 0000-0001-6083-4013Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Adam B. Castoreno· 1 shared Alexandria M. DoerfleriD· 1 shared Ayrea E. HurleyiD· 1 shared Christine BeetoniD· 1 shared Christopher J. WalkeyiD· 1 shared Gang BaoiD· 1 shared Gang LiiD· 1 shared Ivan ZlateviD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Adam B. Castoreno

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1 paper

Recent·Most cited

GeneticsScience Translational MedicinePeer-reviewedFeb 12, 2025

In vivo expansion of gene-targeted hepatocytes through transient inhibition of an essential gene

Marco De Giorgi, So Hyun Park, Adam B. Castoreno…·William R. Lagor

This paper introduces a method to increase the proportion of correctly repaired hepatocytes in the liver through transient gene inhibition and transgene delivery, achieving a 25% increase in targeted cells and five-fold transgene expression.

8 citations

mouseCRISPR screen

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