Cancer BiologybioRxivPreprint
Tumor Cells Enriched for Interferon and Inflammatory Programs Pre-Exist in High Grade Serous Ovarian Cancer and are Proportionately Significantly Increased Post Chemotherapy
Boris J. N. Winterhoff, Nomeda Girnius, Muyi Liu…·Joan S. Brugge
The paper identifies pre-existing tumor cells with interferon and inflammatory programs in HGSOC that increase after chemotherapy, suggesting a therapeutic window for intervention.