Author

Dennis J. Slamon

University of California, Los AngelesORCID 0000-0002-6330-498XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Joan S. BruggeiD· 2 shared André SchultziD· 1 shared Andy NelsoniD· 1 shared Anil KorkutiD· 1 shared Aylin Z. HenstridgeiD· 1 shared Boris J. N. WinterhoffiD· 1 shared Christopher T. BonifaceiD· 1 shared Erika von EuwiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Joan S. BruggeORCID

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2 papers

Recent·Most cited

Tumor Cells Enriched for Interferon and Inflammatory Programs Pre-Exist in High Grade Serous Ovarian Cancer and are Proportionately Significantly Increased Post Chemotherapy

Boris J. N. Winterhoff, Nomeda Girnius, Muyi Liu, Jaeyoung Kang, Mihir Shetty, M. Angie Martinez-Gakidis, Weiyi Xu, Mayura Thomas, Linna Lahmadi, Aylin Z. Henstridge, Pilar Baldominos, Shobhana Talukdar, Zenas Chang, Jordan N. Mattson, Morgan Gruner, , Joan S. Brugge

The paper identifies pre-existing tumor cells with interferon and inflammatory programs in HGSOC that increase after chemotherapy, suggesting a therapeutic window for intervention.

bioRxiv · Jun 24, 2025 · PreprintCancer Biology

Large-scale Characterization of Drug Responses of Clinically Relevant Proteins in Cancer Cell Lines

Wei Zhao, Jun Li, Mei-Ju M. Chen, Yikai Luo, Zhenlin Ju, Nicole K. Nesser, Katie Johnson-Camacho, Christopher T. Boniface, Yancey Lawrence, Nupur T. Pande, Michael A. Davies, Meenhard Herlyn, Taru E. Muranen, Ioannis K. Zervantonakis, Erika von Euw, , Han Liang

The paper compiles protein response data from cancer cell lines to drug perturbations, showing improved drug sensitivity prediction and building a protein-drug connectivity map with an accessible data portal.

Cancer Cell · Nov 5, 2020Peer-reviewedSystems Biology