Author

Aylin Z. Henstridge

Harvard UniversityORCID 0000-0003-1517-8306Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

Ahmed M. ElhossinyiD· 1 shared Allison R. SchulmaniD· 1 shared Andy NelsoniD· 1 shared Arvind U.K. RaoiD· 1 shared Boris J. N. WinterhoffiD· 1 shared Costas Andreas LyssiotisiD· 1 shared Dennis J. SlamoniD· 1 shared Eileen S. CarpenteriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Ahmed M. ElhossinyORCID

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2 papers

Recent·Most cited

Cancer BiologyCancer ResearchPeer-reviewedSep 21, 2026

Longitudinal Analysis of Matched Patient Biospecimens Reveals Neural Reprogramming of Cancer-Associated Fibroblasts Following Chemotherapy in Pancreatic Cancer

Aylin Z. Henstridge, Peter A. Azorsa, Nandini Arya…·Eileen S. Carpenter

The paper analyzes matched pre- and post-chemotherapy biospecimens in pancreatic cancer, revealing that cancer-associated fibroblasts undergo neural reprogramming, characterized by axonal guidance gene enrichment, which may contribute to chemoresistance and tumor progression.

1 citation

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintJun 24, 2025

Tumor Cells Enriched for Interferon and Inflammatory Programs Pre-Exist in High Grade Serous Ovarian Cancer and are Proportionately Significantly Increased Post Chemotherapy

Boris J. N. Winterhoff, Nomeda Girnius, Muyi Liu…·Joan S. Brugge

The paper identifies pre-existing tumor cells with interferon and inflammatory programs in HGSOC that increase after chemotherapy, suggesting a therapeutic window for intervention.

5 citations

humanscRNA-seq

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