Author

Boris J. N. Winterhoff

University of MinnesotaORCID 0000-0002-1334-8650Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

Ronny DrapkiniD· 3 shared Gottfried E. KonecnyiD· 2 shared Adrianna L. BartolomucciiD· 1 shared Akshaya Vijaya AnnapragadaiD· 1 shared Alice C. EastmaniD· 1 shared Andrew Nelson· 1 shared Andy NelsoniD· 1 shared Aylin Z. HenstridgeiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersCancer Biology

Ronny DrapkinORCID

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3 papers

Recent·Most cited

Structural variation in repeat elements is widespread in normal human tissues and in tumorigenesis

Akshaya Vijaya Annapragada, James White, Hope Orjuela, Adrianna L. Bartolomucci, Alice C. Eastman, Shashikant Koul, Kauí Patrício Lebarbenchon, Daniel C. Bruhm, Sarah Short, Keerti Boyapati, Noushin Niknafs, Carter Norton, Vishruth Girish, Nicholas A. Vulpescu, Sofia Velculescu, , Victor E. Velculescu

The paper identifies widespread mosaic structural variants in normal human tissues and tumors, with repeat-mediated variants impacting functional elements and enabling noninvasive tumor monitoring through cell-free DNA.

bioRxiv · Sep 28, 2026 · PreprintGenomics

Tumor Cells Enriched for Interferon and Inflammatory Programs Pre-Exist in High Grade Serous Ovarian Cancer and are Proportionately Significantly Increased Post Chemotherapy

Boris J. N. Winterhoff, Nomeda Girnius, Muyi Liu, Jaeyoung Kang, Mihir Shetty, M. Angie Martinez-Gakidis, Weiyi Xu, Mayura Thomas, Linna Lahmadi, Aylin Z. Henstridge, Pilar Baldominos, Shobhana Talukdar, Zenas Chang, Jordan N. Mattson, Morgan Gruner, , Joan S. Brugge

The paper identifies pre-existing tumor cells with interferon and inflammatory programs in HGSOC that increase after chemotherapy, suggesting a therapeutic window for intervention.

bioRxiv · Jun 24, 2025 · PreprintCancer Biology

ZNFX1 is a Novel Master Regulator in Epigenetically-induced Pathogen Mimicry and Inflammasome Signaling in Cancer

Lora Stojanovic, Rachel Abbotts, Kaushlendra K. Tripathi, Collin M. Coon, Saranya Rajendran, Elnaz Abbasi Farid, Galen H. Hostetter, Joseph W. Guarnieri, Douglas C. Wallace, Sheng Liu, Jun Wan, Gennaro Calendo, Rebecca Marker, Zahra Gohari, Mohammed Inayatullah, , Feyruz Virgilia Rassool

This study identifies ZNFX1 as a master regulator of epigenetically-induced pathogen mimicry and inflammasome signaling in ovarian cancer, linking its expression to disease progression and survival.

Cancer Research · Jan 13, 2025Peer-reviewedCancer Biology