Author

Nomeda Girnius

Harvard UniversityORCID 0000-0002-7267-5950Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Andy NelsoniD· 1 shared Anniina FärkkiläiD· 1 shared Antti ElloneniD· 1 shared Aylin Z. HenstridgeiD· 1 shared Boris J. N. WinterhoffiD· 1 shared Caitlin E. MillsiD· 1 shared Dennis J. SlamoniD· 1 shared Eloise WithnelliD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Andy NelsonORCID

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2 papers

Recent·Most cited

Integrative single-cell and spatial mapping of oxidative stress response uncovers GCLC+ mesenchymal tumor cell state linked with favorable outcomes in triple negative breast cancer

Nomeda Girnius, Tuulia Vallius, Wenqing Chen, Inga-Maria P. Launonen, Sara Palomino‐Echeverría, Jia‐Ren Lin, Caitlin E. Mills, Saila Kauppila, Pauliina Kronqvist, Antti Ellonen, Merja Perälä, Eloise Withnell, Yu‐An Chen, Maria Secrier, Sandro Santagata, , Anniina Färkkilä

The paper maps oxidative stress response in TNBC using single-cell and spatial data, identifying GCLC+ mesenchymal tumor cells linked to better patient outcomes.

bioRxiv · Nov 6, 2025 · PreprintCancer Biology

Tumor Cells Enriched for Interferon and Inflammatory Programs Pre-Exist in High Grade Serous Ovarian Cancer and are Proportionately Significantly Increased Post Chemotherapy

Boris J. N. Winterhoff, Nomeda Girnius, Muyi Liu, Jaeyoung Kang, Mihir Shetty, M. Angie Martinez-Gakidis, Weiyi Xu, Mayura Thomas, Linna Lahmadi, Aylin Z. Henstridge, Pilar Baldominos, Shobhana Talukdar, Zenas Chang, Jordan N. Mattson, Morgan Gruner, , Joan S. Brugge

The paper identifies pre-existing tumor cells with interferon and inflammatory programs in HGSOC that increase after chemotherapy, suggesting a therapeutic window for intervention.

bioRxiv · Jun 24, 2025 · PreprintCancer Biology