Jeffrey D. Axelrod

The paper investigates how cluster assembly dynamics contribute to planar cell polarity polarization by analyzing protein monomer counts in live animals and using mathematical modeling.

The paper shows cancer cells redistribute mitochondria to sustain immunosuppressive ecosystems, reprogramming immune cells and enhancing their own metabolic resilience.

This study shows that Planar Cell Polarity (PCP) signaling can polarize cells autonomously, without requiring intercellular feedback, and identifies feedback pathways that operate cell-autonomously.

This study shows Flamingo (Fmi) is required for cell competition in Drosophila, functioning in both malignant and healthy contexts through a mechanism independent of planar cell polarity.

This paper develops automated workflows for counting cell nuclei in Drosophila imaginal discs, including handling twin-spot labeled nuclei using machine learning.

The paper identifies Pp1-87B as a regulator of core PCP signaling by modulating Van Gogh subcellular localization and dephosphorylation in Drosophila wings.