Author

Ruoxuan Li

Johns Hopkins UniversityORCID 0000-0001-6095-7945Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Ruoxuan Li1 paper · Chinese Academy of Sciences

Biology Disciplines

Click to filter author papers

Neuroscience· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:imaging· 3 Organism:mouse· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Aaron Kakazu· 3 shared Minmin Yao· 3 shared Wenzhen DuaniD· 3 shared Yuxiao OuyangiD· 3 shared Zhiliang WeiiD· 3 shared Haitong WangiD· 2 shared Hanzhang LuiD· 2 shared Lida DuiD· 2 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Aaron Kakazu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

NeuroscienceExperimental NeurologyPeer-reviewedSep 12, 2025

Progressively reduced cerebral oxygen metabolism and elevated plasma NfL levels in the zQ175DN mouse model of Huntington disease

Qian Wu, Minmin Yao, Hongshuai Liu…·Wenzhen Duan

This study characterizes the progression of the zQ175DN mouse model of Huntington disease, identifying early biomarkers like brain volume loss and plasma NfL elevation.

2 citations

𝕏 PostBluesky

NeurosciencebioRxivPreprintApr 23, 2025

Cell type-specific contributions to impaired blood-brain barrier and cerebral metabolism in presymptomatic 5XFAD mice

Minmin Yao, Na Sun, Raleigh M. Linville…·Wenzhen Duan

The paper identifies cell type-specific transcriptomic changes in 5XFAD mice that link BBB dysfunction and metabolic dysregulation to early AD pathogenesis.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky

NeuroscienceNeurobiology of DiseasePeer-reviewedOct 21, 2024

Senolytic therapy preserves blood-brain barrier integrity and promotes microglia homeostasis in a tauopathy model

Minmin Yao, Zhiliang Wei, Jonathan Scharff Nielsen…·Wenzhen Duan

This study shows that senolytic therapy with D+Q preserves BBB integrity and improves cognitive function in a tauopathy mouse model.

35 citationstop 1%

𝕏 PostBluesky