Author

Lida Du

Johns Hopkins UniversityORCID 0000-0001-8598-6224Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:imaging· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

Wenzhen DuaniD· 3 shared Aaron Kakazu· 2 shared Haitong WangiD· 2 shared Hanzhang LuiD· 2 shared Minmin Yao· 2 shared Ruoxuan LiiD· 2 shared Yuan Zhou· 2 shared Yuxiao OuyangiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersNeuroscience

Wenzhen DuanORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 7, 2026

Computer vision-aided locomotor behavioral analysis identifies therapeutic motor signatures in a mouse model of Huntington disease

Lida Du, Zhenyu Wang, Qian Wu…·Wenzhen Duan

The paper introduces a computer vision framework to analyze fine motor behaviors in HD mice, identifying disease-specific motor signatures and a scoring system to assess therapeutic effects.

DOI 10.64898/2026.09.03.749147

mouseimaging

𝕏 PostBluesky

NeurosciencebioRxivPreprintApr 23, 2025

Cell type-specific contributions to impaired blood-brain barrier and cerebral metabolism in presymptomatic 5XFAD mice

Minmin Yao, Na Sun, Raleigh M. Linville…·Wenzhen Duan

The paper identifies cell type-specific transcriptomic changes in 5XFAD mice that link BBB dysfunction and metabolic dysregulation to early AD pathogenesis.

2 citations

mousebulk RNA-seq

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NeuroscienceNeurobiology of DiseasePeer-reviewedOct 21, 2024

Senolytic therapy preserves blood-brain barrier integrity and promotes microglia homeostasis in a tauopathy model

Minmin Yao, Zhiliang Wei, Jonathan Scharff Nielsen…·Wenzhen Duan

This study shows that senolytic therapy with D+Q preserves BBB integrity and improves cognitive function in a tauopathy mouse model.

35 citationstop 1%

mouseimaging

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