Author

Prasath Manogaran

Cleveland ClinicORCID 0000-0001-6105-7818Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Ajay H. ZalavadiaiD· 1 shared Andrei I. IvanoviD· 1 shared Andrew Deng· 1 shared Naseer SangwaniD· 1 shared Nayden G. NaydenoviD· 1 shared Susana LechugaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperCell Biology

Ajay H. ZalavadiaORCID

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintOct 5, 2026

SETD3 ACTIN HISTIDINE METHYLTRANSFERASE REGULATES INTESTINAL EPITHELIAL BARRIER INTEGRITY AND MUCOSAL INFLAMMATION

Prasath Manogaran, Nayden G. Naydenov, Susana Lechuga…·Andrei I. Ivanov

This study shows that SETD3 methylates actin, enhancing F-actin polymerization and protecting intestinal epithelial barrier integrity, and its loss worsens inflammation and permeability.

DOI 10.64898/2026.10.02.756302

humanmouse

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