Susana Lechuga

This study shows that SETD3 methylates actin, enhancing F-actin polymerization and protecting intestinal epithelial barrier integrity, and its loss worsens inflammation and permeability.

This study shows that NM IIA limits A/E bacterial colonization by inhibiting actin pedestal formation, while NM IIC does not play a similar role.

This study investigates the role of SEPT9 in intestinal epithelial barrier integrity and inflammation, finding that its loss disrupts tight junctions and increases susceptibility to colitis.