Ajay H. Zalavadia

This study shows that SETD3 methylates actin, enhancing F-actin polymerization and protecting intestinal epithelial barrier integrity, and its loss worsens inflammation and permeability.

This study shows that NM IIA limits A/E bacterial colonization by inhibiting actin pedestal formation, while NM IIC does not play a similar role.

This study shows that 4-ethylphenylsulfate (4EPS) interacts with AT1R, lowers blood pressure, and reduces aortic aneurysm severity in mice.

This study shows chronic ER stress induces β-cell plasticity, but excessive stress leads to identity loss and is linked to T1D progression.

This study shows that Ifit2 deficiency in mice leads to severe viral spread and demyelination in the spinal cord during chronic RSA59 infection.