Synthetic BiologybioRxivPreprint
Harnessing Diversity Generating Retroelements for in vivo targeted hyper-mutagenesis
Raphaël Laurenceau, Paul Rochette, Elena Lopez-Rodriguez…·David Bikard
This paper introduces DGRec, a method using DGRs to enable targeted hyper-mutagenesis in E. coli, creating diverse variants that allow evasion of phage infection.
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