Author

Scott T.C. Shepherd

Institute of Cancer ResearchORCID 0000-0001-6208-173XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Samra TurajliciD· 3 shared Anne-Laure CattiniD· 2 shared Annika FendleriD· 2 shared Daqi DengiD· 2 shared Fiona ByrneiD· 2 shared Hugang FengiD· 2 shared Jiahao Wang· 2 shared Omar Bouricha· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Samra TurajlicORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 3, 2026

Distinct functions of PBRM1 and BAP1 reconcile the course of kidney cancer evolution and disease progression

Daqi Deng, Hugang Feng, Annika Fendler…·Samra Turajlic

This study identifies distinct molecular programs in PBRM1- and BAP1-driven ccRCC, explaining their different evolutionary trajectories and clinical outcomes.

DOI 10.64898/2026.04.30.721837

humanbulk RNA-seq

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GenomicsbioRxivPreprintApr 25, 2025

Genome-wide Chromosome-specific Aneuploidy Engineering and Phenotypic Characterization with CRISPR-Taiji

Hugang Feng, Daqi Deng, Rashmi Dahiya…·Samra Turajlic

The paper introduces CRISPR-Taiji to engineer chromosome-specific aneuploidy and characterizes its transcriptomic effects, linking aneuploidy to ccRCC phenotypes.

1 citation

humanscRNA-seq

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GenomicsNature GeneticsPeer-reviewedJul 1, 2024

Saturation Genome Editing Resolves the Functional Spectrum of Pathogenic VHL Alleles

Megan Buckley, Chloé Terwagne, Athina Ganner…·Gregory M. Findlay

This study uses Saturation Genome Editing to functionally assess VHL variants, identifying pathogenic alleles and their mechanisms in cancer.

62 citationstop 1%

humanwhole-exome sequencing

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