Author
The Francis Crick InstituteORCID 0000-0002-1876-5621Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Daqi Deng, Hugang Feng, Annika Fendler…·Samra Turajlic
This study identifies distinct molecular programs in PBRM1- and BAP1-driven ccRCC, explaining their different evolutionary trajectories and clinical outcomes.
Hugang Feng, Daqi Deng, Rashmi Dahiya…·Samra Turajlic
The paper introduces CRISPR-Taiji to engineer chromosome-specific aneuploidy and characterizes its transcriptomic effects, linking aneuploidy to ccRCC phenotypes.
Karen A. Lane, Alison Harrod, Lillian Wu…·Jessica A. Downs
This study identifies PBAF as a protector of centromere and pericentromere structure, showing that PBRM1 loss leads to centromere fragility and therapeutic vulnerability.