Alexandre Djiane

This study shows that FuFA-F2 supplementation prevents muscle atrophy and preserves muscle function in a cancer cachexia model without affecting tumor growth.

This study identifies MDM2 stabilization of NICD in response to platinum chemotherapy in NSCLC, showing that targeting MDM2 and NICD improves survival and reduces tumor growth.

This study identifies E(spl)m4 as an inhibitor of Traf4 signaling in Drosophila, preventing JNK activation and cell delamination without affecting Adherens Junctions.

This paper identifies Ilp8 and Upd3 from Drosophila larval tumours as factors that deplete intestinal stem-cell-like cells and disrupt niche organization during cachexia.

The paper investigates how loss of epithelial polarity and Notch signaling interact in Drosophila neoplastic growth, showing specific transcriptional dependencies and novel factors involved.