Meredith D. Hartley

This study quantifies longitudinal CNS cholesterol and ester levels in a mouse model during myelination, demyelination, and remyelination, revealing impaired cholesterol recovery after demyelination.

This study compares microglial responses to myelin damage in the brain and spinal cord, finding that brain microglia support remyelination while spinal cord microglia exhibit impaired repair.

This study shows that cholesterol ester levels rise during demyelination and decrease during remyelination in the brain but remain elevated in the spinal cord, suggesting a role for cholesterol esters in demyelinating diseases.

This study uses lipidomic analysis to show differences in remyelination capabilities between brain and spinal cord in a mouse model of demyelination.