Eden P. Go

Quantitative determination of longitudinal CNS cholesterol loss during myelin damage and repair

This study quantifies longitudinal CNS cholesterol and ester levels in a mouse model during myelination, demyelination, and remyelination, revealing impaired cholesterol recovery after demyelination.

Analysis of glycosylation and disulfide bonding of wild-type SARS-CoV-2 spike glycoprotein

The paper analyzes glycosylation and disulfide bonding of wild-type SARS-CoV-2 spike glycoprotein, finding that Golgi processing leads to complex N-glycans and partial infectivity in a Cys15Phe mutant.

Asymmetric structures and conformational plasticity of the uncleaved full-length human immunodeficiency virus (HIV-1) envelope glycoprotein trimer

This study investigates the conformational plasticity of the uncleaved HIV-1 Env trimer and its implications for antibody recognition and Env cleavage.

Structural insights into the conformational plasticity of the full-length trimeric HIV-1 envelope glycoprotein precursor

This study uses cryo-EM to reveal two conformational states of the HIV-1 Env precursor, explaining its plasticity and implications for immune response.