Author

Rashmi Binjawadagi

University of Kansas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Hiroko KobayashiiD· 3 shared Jenna M. Williams· 3 shared Meredith D. HartleyiD· 3 shared Nishama De Silva MohottiiD· 3 shared Disni DedunupitiyaiD· 2 shared A. Denise R. GarciaiD· 1 shared Ali MostafaiD· 1 shared Ana Maria MansillaiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersNeuroscience

Hiroko KobayashiORCID

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Author profile →

4 papers

Recent·Most cited

Mechanisms regulating combination effect of antibody-drug conjugates and cancer immunotherapy

Şehmus Tohumeken, Ali Mostafa, Rashmi Binjawadagi, Mimi Mai, Ana Paucarmayta, Ana Maria Mansilla, Christine Youn, E Sally Chang, Pooja Shah, Huiyanangel Chow, Wileashire Moulton, Xiaokang Luo, Kerlene Berwick Tam, Matthew Flynn, Leslie K. Wetzel, , Dmitry I. Gabrilovich

This paper investigates the mechanisms of ADC-immunotherapy combinations, finding that ADC-induced autophagy upregulates TNFR and M6PR, driving antitumor effects through TNF and granzyme B pathways.

bioRxiv · Jul 22, 2026 · PreprintImmunology

Quantitative determination of longitudinal CNS cholesterol loss during myelin damage and repair

Disni Dedunupitiya, Eden P. Go, Travis Witte, Ashlynn Elliott, Nishama De Silva Mohotti, Jenna M. Williams, Hiroko Kobayashi, Rashmi Binjawadagi, Heather Desaire, Meredith D. Hartley

This study quantifies longitudinal CNS cholesterol and ester levels in a mouse model during myelination, demyelination, and remyelination, revealing impaired cholesterol recovery after demyelination.

bioRxiv · Jun 9, 2026 · PreprintNeuroscience

Temporal dynamics of CNS cholesterol esters correlate with demyelination and remyelination

Nishama De Silva Mohotti, Jenna M. Williams, Rashmi Binjawadagi, Hiroko Kobayashi, Disni Dedunupitiya, Jack M. Petersen, A. Denise R. Garcia, Meredith D. Hartley

This study shows that cholesterol ester levels rise during demyelination and decrease during remyelination in the brain but remain elevated in the spinal cord, suggesting a role for cholesterol esters in demyelinating diseases.

ACS Chemical Neuroscience · Dec 9, 2025Peer-reviewedNeuroscience

Lipidomic analysis reveals differences in the extent of remyelination in the brain and spinal cord

Nishama De Silva Mohotti, Hiroko Kobayashi, Jenna M. Williams, Rashmi Binjawadagi, Michel P. Evertsen, Ethan G. Christ, Meredith D. Hartley

This study uses lipidomic analysis to show differences in remyelination capabilities between brain and spinal cord in a mouse model of demyelination.

Journal of Proteome Research · Nov 29, 2023Peer-reviewedNeuroscience