Author

Elif Öykü Cakir

Columbia University Irving Medical CenterORCID 0000-0001-6237-2801Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1 Organism:zebrafish· 1

Frequent Co-Authors

Andrew F. TeichiD· 1 shared Annie LeeiD· 1 shared Badri Narayan VardarajaniD· 1 shared Bengisu TurgutalpiD· 1 shared Çağhan KızıliD· 1 shared Carsten WerneriD· 1 shared Dörthe JülichiD· 1 shared Dylan MurphyiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Andrew F. TeichORCID

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1 paper

Recent·Most cited

APOE-ϵ4-induced Fibronectin at the blood-brain barrier is a conserved pathological mediator of disrupted astrocyte-endothelia interaction in Alzheimer's disease

Prabesh Bhattarai, Elanur Yılmaz, Elif Öykü Cakir, Hüseyin Tayran, Imdadul Haq, Dylan Murphy, Jonah Nadelmann Keller, Quentin Le Grand, Jacqueline Eschbach, Hilal Çelikkaya, Mehmet İlyas Coşacak, Hande Yüceer, Annie Lee, Verena Claudia Haage, Yiyi Ma, , Çağhan Kızıl

This paper identifies APOE-ϵ4-induced fibronectin accumulation at the blood-brain barrier as a key mediator of astrocyte-endothelial dysfunction in Alzheimer's disease, highlighting it as a potential therapeutic target.

Nature Aging · Sep 11, 2026Peer-reviewedCell Biology