Mark Hedley Vickers

The paper identifies ASD-associated SNPs in fetal and adult cortex tissues and links them to regulatory processes and pathways, highlighting differences in their impact across developmental stages.

This study identifies 33 genes and 62 pathways impacted by GWAS SNPs associated with psychiatric disorders and cognitive functioning, revealing shared regulatory mechanisms despite no common SNPs or eQTLs.

This study shows TNF-α induces different cell cycle gene responses in promyelocytic and granulocytic HL-60/S4 cells, with promyelocytes showing upregulation and granulocytes downregulation, and granulocytes shifting towards a macrophage-like transcriptome.

The paper uses Hi-C and RNA-seq to identify and compare structural variants in HL-60 and HL-60/S4 cell lines, finding novel SVs and differences in their stability.

The paper shows that neutrophil migration through small pores disrupts inactive chromatin organization, as revealed by transcriptomic and Hi-C analyses.

This study identifies immune regulatory networks influenced by T1D-associated genetic variants using 3D genome organization and gene expression data.