Author

Anna-Sophia Krebs

École Polytechnique Fédérale de LausanneORCID 0000-0001-6244-9899Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Alessio CiulliiD· 1 shared Diane L. HaakonseniD· 1 shared Emiliya PoghosyaniD· 1 shared Gabriella ColluiD· 1 shared Gajanan J. SatheiD· 1 shared Joachim LingneriD· 1 shared Jonathan SchneideriD· 1 shared Juan Carlos SilvaiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

Alessio CiulliORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintMar 3, 2026

Medulloblastoma-Associated KBTBD4 Mutations Disrupt PP2A-A Orphan Quality Control

Regina Baur, Laura A. Hehl, Gajanan J. Sathe…·Nicolas H. Thomä

This study identifies PP2A-A as a target of CRL3KBTBD4, showing that KBTBD4 mutations disrupt PP2A quality control and contribute to medulloblastoma by altering phospho-dependent signaling.

DOI 10.64898/2026.03.02.709011

humanproteomics

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Molecular BiologyStructurePeer-reviewedSep 28, 2021

Chimeric single α-helical domains as rigid fusion protein connections for protein nanotechnology and structural biology

Gabriella Collu, Tobias Bierig, Anna-Sophia Krebs…·Roger Benoit

The paper demonstrates that the ER/K motif (SAH) can rigidly connect protein domains, enabling the formation of ordered crystals and new applications in protein nanotechnology.

17 citations

protein structureexperimental assay

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