Author

Diane L. Haakonsen

Howard Hughes Medical InstituteORCID 0009-0006-1690-4970Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Assay:proteomics· 1

Frequent Co-Authors

Michael RapéiD· 2 shared Alessio CiulliiD· 1 shared Alex ZelteriD· 1 shared Anna-Sophia KrebsiD· 1 shared Gajanan J. SatheiD· 1 shared Joachim LingneriD· 1 shared Jonathan SchneideriD· 1 shared Juan Carlos SilvaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

Michael RapéORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintMar 3, 2026

Medulloblastoma-Associated KBTBD4 Mutations Disrupt PP2A-A Orphan Quality Control

Regina Baur, Laura A. Hehl, Gajanan J. Sathe…·Nicolas H. Thomä

This study identifies PP2A-A as a target of CRL3KBTBD4, showing that KBTBD4 mutations disrupt PP2A quality control and contribute to medulloblastoma by altering phospho-dependent signaling.

DOI 10.64898/2026.03.02.709011

humanproteomics

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BiochemistryNaturePeer-reviewedMay 6, 2025

The molecular basis of integrated stress response silencing

Zhi Yang, Diane L. Haakonsen, Michael Heider…·Michael Rapé

This study determines the structure of the human E3 ligase SIFI, revealing its mechanism for ubiquitinating multiple substrates to silence the integrated stress response.

30 citationstop 1%

humanexperimental assay

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