Author

Dylan M. Lynch

University College LondonORCID 0000-0001-6245-9704Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Organism:zebrafish· 1

Frequent Co-Authors

Alena KroupovaiD· 1 shared Alessio CiulliiD· 1 shared Anastasia A. LabudinaiD· 1 shared Andre J. WijayaiD· 1 shared Christoph GöbliD· 1 shared Darren DarreniD· 1 shared David ZollmaniD· 1 shared Denzel Gonzales· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

Alena KroupovaORCID

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2 papers

Recent·Most cited

Developmental BiologybioRxivPreprintAug 21, 2026

Loss of cohesin subunit Stag1 in zebrafish limits cell cycle progression and is compensated by altered BMP signalling and metabolic pathways

Dylan M. Lynch, Anastasia A. Labudina, Sarada Ketharnathan…·Michael Meier

This study shows that loss of Stag1 in zebrafish impairs cell cycle progression and activates p53, but is compensated by changes in BMP signaling and metabolism.

DOI 10.64898/2026.08.20.745648

zebrafishexperimental assay

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BiochemistryNature CommunicationsPeer-reviewedOct 15, 2024

Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders

Alena Kroupova, Valentina A. Spiteri, Zoe J. Rutter…·Alessio Ciulli

The paper introduces CRBNmidi, a Cereblon construct that enables high-resolution structural and biophysical studies of degraders without requiring DDB1 co-expression.

53 citationstop 2%

protein structureexperimental assay

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