Author

Johanna Hardin

Pomona CollegeORCID 0000-0001-6251-1955Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Danae SchulziD· 2 shared Ethan C. AshbyiD· 2 shared Anya Porter· 1 shared Carrie Saada· 1 shared ERIC K. Y. TANGiD· 1 shared Geneva MilleriD· 1 shared Hannah L. BettsiD· 1 shared Jennifer L. HavensiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersMolecular Biology

Danae SchulzORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJan 9, 2023

Chemical inhibition of bromodomain proteins in insect stage African trypanosomes perturbs silencing of the Variant Surface Glycoprotein repertoire and results in widespread changes in the transcriptome

Ethan C. Ashby, Jennifer L. Havens, Johanna Hardin, Danae Schulz

This study shows that inhibiting bromodomain proteins in insect stage African trypanosomes causes transcriptome changes and disrupts VSG gene silencing, similar to developmental progression.

DOI 10.1101/2023.01.09.523188

bulk RNA-seqexperimental assay

𝕏 PostBluesky

Molecular BiologymSpherePeer-reviewedJun 1, 2022

Genomic occupancy of the bromodomain protein Bdf3 is dynamic during differentiation of African trypanosomes from bloodstream to procyclic forms

Ethan C. Ashby, Lucinda Paddock, Hannah L. Betts…·Danae Schulz

The paper investigates dynamic changes in Bdf3 chromatin occupancy during Trypanosoma brucei differentiation from bloodstream to insect stage, finding increased occupancy at genes involved in surface protein remodeling.

10 citations

ArabidopsisChIP-seq

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