Christopher A. Johnston

This study investigates phase transitions in biological condensates formed by the mitotic spindle regulator Mud and related proteins, revealing liquid-to-solid transitions and their molecular mechanisms.

This study identifies molecular and evolutionary determinants for ALDODOM protein interactions, showing that a C-terminal helix and conserved residues enable Mud binding in Drosophila Adducin.

The paper uses Drosophila to model a human Nkx2.5 variant, showing it causes DNA binding defects and reduced cofactor interaction, leading to cardiac differentiation issues.

The paper identifies Mef2 and Tinman as regulators of heart lumen enlargement in Drosophila by activating the collagen gene Multiplexin.