Louise S. Matheson

This study identifies ZFP36L1 and ZFP36L2 as RNA-binding proteins that regulate the G2-M checkpoint in GC B cells to prevent replication stress and maintain genome stability.

This study shows DDX1 promotes B-cell proliferation in germinal centres by enhancing mRNA translation through tRNA ligase activity, crucial for affinity maturation.

ORFLine identifies and characterizes small open reading frames in mouse lymphocytes, revealing novel secreted micropeptides.

This study shows that Zfp36l1 and Zfp36l2 regulate retinal development by balancing proliferation and differentiation, with their loss causing reduced proliferation and increased differentiation in the retina.