Chuanfu Dong

This study shows that ISKNV-pORF71 hijacks VDAC2 from mitochondria to the nucleus, disrupting mitochondrial membrane permeability and enhancing apoptosis during infection.

This study identifies mfTfR1 as the entry receptor for SDDV, demonstrating its role in clathrin-mediated endocytosis and viral entry.

This study uses single-cell RNA sequencing to analyze the response of mandarin fish pyloric caecum to MRV infection, revealing serositis as the cause of ascites.

This study shows SDDV induces ferroptosis by targeting TfR1, enhancing viral infection, and suggests ferroptosis inhibition as a therapeutic strategy.

This study identifies peripheral B lymphocytes as a viral reservoir for persistent and covert Mandarinfish Ranavirus (MRV) infection, revealing a unique reactivation mechanism distinct from other ranaviruses.