Author

Toshifumi Sugatani

Washington University in St. LouisORCID 0000-0001-6282-7554Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Roberto CivitelliiD· 2 shared Ariella L. G. Coler-ReillyiD· 1 shared Francesca FontanaiD· 1 shared Giulia LeanzaiD· 1 shared Hillary Fujimoto· 1 shared Ignacio A. Portales CastilloiD· 1 shared Kate Yeo· 1 shared Marco A Campioli· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

Roberto CivitelliORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 22, 2025

N-cadherin in osteolineage cells restrains breast cancer cell growth via inhibition of a PI3K-dependent, Tgf-β1-driven feed-forward loop

Toshifumi Sugatani, Kate Yeo, Marco A Campioli…·Roberto Civitelli

This study shows that N-cadherin in osteolineage cells inhibits breast cancer growth by blocking a Tgf-β1-driven feed-forward loop involving PI3K-Akt-β-catenin signaling.

DOI 10.1101/2025.10.22.683948

mousebulk RNA-seq

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PhysiologyJCI InsightPeer-reviewedFeb 13, 2024

Connexin43 in mesenchymal lineage cells regulates body adiposity and energy metabolism in mice

Seung-Yon Lee, Francesca Fontana, Toshifumi Sugatani…·Roberto Civitelli

This study shows that Cx43 in mesenchymal lineage cells reduces body adiposity and improves metabolic health in mice on a high-fat diet.

12 citations

mouseexperimental assay

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