Author

Melissa R. Alcorn

University of California, Santa BarbaraORCID 0000-0001-6284-3255Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Chee Kiang EweiD· 2 shared Joel H. RothmaniD· 2 shared Pradeep M. JoshiiD· 2 shared Yamila N. Torres CleureniD· 2 shared Coco Emma Alma Al-Alami· 1 shared Cricket G. Wood· 1 shared Emily MearsiD· 1 shared Geneva AlokiD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenetics

Chee Kiang EweORCID

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2 papers

Recent·Most cited

Regulation of defective mitochondrial DNA accumulation and transmission in C. elegans by the programmed cell death and aging pathways

Sagen E. Flowers, Rushali Kothari, Yamila N. Torres Cleuren, Melissa R. Alcorn, Chee Kiang Ewe, Geneva Alok, Samantha L Fiallo, Pradeep M. Joshi, Joel H. Rothman

This study shows that programmed cell death and aging pathways regulate mtDNA quality control and transmission in C. elegans by affecting the accumulation of a defective mtDNA mutation.

eLife · Sep 19, 2023Peer-reviewedGenetics

Extensive intraspecies cryptic variation in an ancient embryonic gene regulatory network

Yamila N. Torres Cleuren, Chee Kiang Ewe, Kyle C Chipman, Emily Mears, Cricket G. Wood, Coco Emma Alma Al-Alami, Melissa R. Alcorn, Thomas L. Turner, Pradeep M. Joshi, Russell G. Snell, Joel H. Rothman

The paper identifies cryptic variation in the C. elegans endoderm gene regulatory network, showing that some embryos can develop endoderm without key regulators, while others require them.

eLife · Aug 15, 2019Peer-reviewedGenetics