Yamila N. Torres Cleuren

The paper investigates mitochondrial complex I deficiency in Parkinson's disease muscle biopsies, finding 9% of cases show reduced CI activity without mtDNA abnormalities.

This study shows that programmed cell death and aging pathways regulate mtDNA quality control and transmission in C. elegans by affecting the accumulation of a defective mtDNA mutation.

ORFik is an R/Bioconductor toolkit for analyzing translation data, supporting multiple high-throughput assays and providing over 30 translation-related metrics.

The paper investigates how heritable epigenetic factors contribute to cryptic variation in the requirement for SKN-1 in endoderm development in C. elegans.

The paper shows that trans-splicing of mRNAs links gene transcription to translational control regulated by mTOR in Oikopleura dioica.

The paper characterizes the transcriptome-wide dynamics of translation initiation stages in a higher eukaryote and identifies regulators at each step.

The paper identifies cryptic variation in the C. elegans endoderm gene regulatory network, showing that some embryos can develop endoderm without key regulators, while others require them.

tailfindr estimates poly(A) tail length from Oxford Nanopore long-read sequencing data without alignment, enabling poly(A) analysis in RNA and DNA sequencing.