Ananda B. Amstadter

This study investigates rare copy number variants in PTSD using whole-genome sequencing and biobank data, finding significant associations in specific ancestry groups and gene-sets.

The paper identifies novel CNV loci and dose-dependent gene effects across six psychiatric disorders using genome-wide analysis.

The paper identifies shared and divergent genetic mechanisms across psychiatric disorders using gene-set burden analysis of copy number variants.

The paper examines genetic correlations between PTSD and alcohol-related phenotypes, finding distinct genetic factors for AUD versus alcohol consumption.

This study identifies genetic variants associated with self-reported childhood maltreatment and finds significant genetic correlations with depressive symptoms.

This study shows that chronic repeated predatory stress reduces male mice's response to quinine adulteration of ethanol but not female mice's.

This study identifies ten novel methylation loci associated with PTSD through a meta-analysis of 1,896 cases and controls across ten cohorts, highlighting the AHRR locus and its link to kynurenine levels.

This study conducts the largest GWAS for PTSD, identifying 6 genome-wide significant loci in European and African ancestries and highlighting novel biological pathways.