Isaias Hernández-Verdín

The paper develops and validates a prognostic model using morphologic intratumoral heterogeneity from histopathology slides to predict survival in primary central nervous system lymphoma.

This study identifies the role of mature dendritic cells type 1 in forming, maintaining, and functioning tertiary lymphoid structures in cancer.

h5adify harmonizes metadata from single-cell datasets using neuro-symbolic methods and local LLMs, improving integration and reducing batch effects.

The paper analyzes AID-related mutations across cancers and finds they are associated with better outcomes in ICI-treated patients and contribute to immunogenic neoepitopes.