Author

Karim Labrèche

Sorbonne UniversitéORCID 0000-0002-3164-9406Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Assay:scRNA-seq· 2 Research Focus:batch correction / integration· 1 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Agustí AlentorniD· 2 shared Ahmed IdbaïhiD· 2 shared Isaias Hernández-VerdíniD· 2 shared Abdelmalek MouazeriD· 1 shared Alex DuvaliD· 1 shared Badreddine Mohand OumoussaiD· 1 shared Daniele RamazzottiiD· 1 shared Edgar Degroodt· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioinformatics

Agustí AlentornORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

h5adify: neuro-symbolic metadata harmonizationenables scalable AnnData integration with locallarge language models

Lucas Rincón de la Rosa, Abdelmalek Mouazer, Masoud NAVIDI, Edgar Degroodt, Tamara Künzle, Sylvain Geny, Ahmed Idbaïh, Maïté Verrault, Karim Labrèche, Isaias Hernández-Verdín, Agustí Alentorn

h5adify harmonizes metadata from single-cell datasets using neuro-symbolic methods and local LLMs, improving integration and reducing batch effects.

bioRxiv · Mar 3, 2026 · PreprintBioinformatics

Comparative analysis of CRISPR/Cas9-targeted nanopore sequencing approaches in repeat expansion disorders

Louise Benarroch, Pierre‐Yves Boëlle, Hélène Madry, Badreddine Mohand Oumoussa, Nobuyuki Eura, Ichizo Nishino, Karim Labrèche, Valeriia Gorbunova, Guillaume Bassez, Tanya Stojkovic, Geneviève Gourdon, Gisèle Bonne, Stéphanie Tomé

This study compares CRISPR/Cas9-targeted nanopore sequencing approaches for characterizing repeat expansions in DM1 and OPDM, showing the impact of basecalling strategies and identifying somatic mosaicism and hypermethylation.

Genomics Proteomics & Bioinformatics · Oct 22, 2025Peer-reviewedBioinformatics

Pan-cancer landscape of AID-related mutations, composite mutations and its potential role in the ICI response

Isaias Hernández-Verdín, Kadir Caner Akdemir, Daniele Ramazzotti, Giulio Caravagna, Karim Labrèche, Karima Mokhtari, Khê Hoang‐Xuan, Matthieu Peyre, Franck Bielle, Mehdi Touat, Ahmed Idbaïh, Alex Duval, Marc Sanson, Agustí Alentorn

The paper analyzes AID-related mutations across cancers and finds they are associated with better outcomes in ICI-treated patients and contribute to immunogenic neoepitopes.

bioRxiv · Jun 26, 2021 · PreprintBioinformatics