Mor R. Alkaslasi

The paper identifies ATF2 phosphorylation as a key driver of neuron apoptosis and shows that inhibiting ATF2 protects neurons in culture and in vivo.

This study examines how cortical neurons respond to mild TBI, identifying ATF3 as a marker for stress-responsive neurons and showing that layer V neurons die while layer II/III neurons survive.

This study develops a human iPSC model of axonal degeneration, identifies DLK-dependent mitochondrial fission as a key mechanism, and shows CRISPR-mediated Drp1 depletion protects neurons from degeneration.

This paper presents a cellular taxonomy of the adult human spinal cord using single nucleus RNA-sequencing and spatial transcriptomics, identifying 29 glial and 35 neuronal clusters and highlighting motoneuron vulnerability to ALS.

The paper uses single nucleus RNA sequencing to identify diverse cholinergic neuron types in the adult mouse spinal cord, revealing distinct transcriptomic classes of visceral and skeletal motor neurons.