Author

Matthew Nebiyou

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Anastasia L. Slavutsky· 3 shared Claire E. Le PichoniD· 3 shared Jorge Gómez-Deza· 3 shared Francisco Manuel Nadal-NicolásiD· 2 shared Mor R. AlkaslasiiD· 2 shared Alexandra StavskyiD· 1 shared Ariel Y. ZhangiD· 1 shared Eliza Y. H. Lloyd· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Anastasia L. Slavutsky

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ATF2 phosphorylation is a core transcriptional driver of neuron apoptosis

Jorge Gómez-Deza, Matthew Nebiyou, Lara H. El Touny, Mor R. Alkaslasi, Zhenyu Zuo, Josette J Wlaschin, Francisco Manuel Nadal-Nicolás, Alexandra Stavsky, Xiaotian Zhang, Anastasia L. Slavutsky, Ariel Y. Zhang, Eliza Y. H. Lloyd, Peter M. Hayashi, Nathan Ashby, Mariella G. Brueck, , Claire E. Le Pichon

The paper identifies ATF2 phosphorylation as a key driver of neuron apoptosis and shows that inhibiting ATF2 protects neurons in culture and in vivo.

Neuron · May 19, 2026Peer-reviewedNeuroscience

DLK-dependent axonal mitochondrial fission drives degeneration following axotomy

Jorge Gómez-Deza, Matthew Nebiyou, Mor R. Alkaslasi, Francisco Manuel Nadal-Nicolás, Preethi Somasundaram, Anastasia L. Slavutsky, Wei Li, Michael Emmerson Ward, Trent A. Watkins, Claire E. Le Pichon

This study develops a human iPSC model of axonal degeneration, identifies DLK-dependent mitochondrial fission as a key mechanism, and shows CRISPR-mediated Drp1 depletion protects neurons from degeneration.

Nature Communications · Dec 30, 2024Peer-reviewedNeuroscience

Local production of reactive oxygen species drives vincristine-induced axon degeneration

Jorge Gómez-Deza, Anastasia L. Slavutsky, Matthew Nebiyou, Claire E. Le Pichon

This study identifies a mechanism by which vincristine induces axon degeneration through increased reactive oxygen species production in axons and shows potential therapeutic interventions.

Cell Death and Disease · Dec 8, 2023Peer-reviewedNeuroscience