Peter David Sly

The paper analyzes bacterial diversity and strain dynamics in the infant respiratory microbiome using whole genome sequencing and metagenomics, revealing age-dependent shifts in dominant taxa and expanding reference genomes for airway microbes.

This study identifies genetic, intrinsic, and environmental factors influencing innate immune cytokine responses in four-year-old children, finding strong genetic and inflammatory biomarker associations.

The paper examines prenatal environmental factors affecting CYP19A1 promoter methylation in cord blood using WQS regression, finding associations with bisphenols, sunlight, mould, phthalates, folate, and air pollution.

This study shows prenatal DEHP exposure increases ASD and ADHD symptoms through DNA methylation changes in children.

The paper identifies SNPs with sex-specific effects on lung function traits using UK Biobank data, finding a significant interaction at rs7697189 near HHIP.

The paper identifies three distinct immune development trajectories in childhood using unsupervised clustering, revealing a high-risk atopic cluster associated with allergic diseases.

The paper tracks the upper airway microbiome changes in preschool children and links them to asthma-associated persistent wheeze, showing that bacterial shifts precede viral infections and symptoms in sensitized children.