Author

Howard H.F. Tang

Baker Heart and Diabetes InstituteORCID 0000-0001-6422-0270Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Assay:metagenomics· 1

Frequent Co-Authors

Michael InouyeiD· 3 shared Shu Mei TeoiD· 3 shared James E. GerniD· 2 shared Kathryn E. HoltiD· 2 shared Merci M.H. Kusel· 2 shared Patrick G. HoltiD· 2 shared Peter David SlyiD· 2 shared Robert F. Lemanske· 2 shared

Activity by Year

2017-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersGenomics

Michael InouyeORCID

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3 papers

Recent·Most cited

GenomicsThe American Journal of Human GeneticsPeer-reviewedOct 31, 2019

Multivariate genome-wide association analysis of a cytokine network reveals variants with widespread immune, haematological and cardiometabolic pleiotropy

Artika P. Nath, Scott C. Ritchie, Nastasiya F. Grinberg…·Michael Inouye

This study identifies genetic variants with pleiotropic effects on cytokines and related traits using a multivariate genome-wide association analysis.

47 citations

humanGWAS summary statistics

𝕏 PostBluesky

Systems BiologybioRxivPreprintDec 20, 2017

Non-parametric mixture models identify trajectories of childhood immune development relevant to asthma and allergy

Howard H.F. Tang, Shu Mei Teo, Danielle C. M. Belgrave…·Michael Inouye

The paper identifies three distinct immune development trajectories in childhood using unsupervised clustering, revealing a high-risk atopic cluster associated with allergic diseases.

DOI 10.1101/237073

humanbulk RNA-seq

𝕏 PostBluesky

GeneticsbioRxivPreprintNov 20, 2017

Dynamics of the upper airway microbiome in the pathogenesis of asthma-associated persistent wheeze in preschool children

Shu Mei Teo, Howard H.F. Tang, Danny Mok…·Michael Inouye

The paper tracks the upper airway microbiome changes in preschool children and links them to asthma-associated persistent wheeze, showing that bacterial shifts precede viral infections and symptoms in sensitized children.

6 citations

humanmetagenomics

𝕏 PostBluesky