Dynamics of the upper airway microbiome in the pathogenesis of asthma-associated persistent wheeze in preschool children
Shu Mei Teo, Howard H.F. Tang, Danny Mok, Louise M. Judd, Stephen C. Watts, Kym Pham, Barbara J. Holt, Merci M.H. Kusel, Michael Serralha, Niamh M. Troy, Yury A. Bochkov, Kristine A. Grindle, Robert F. Lemanske, Sebastian Lennox Johnston, James E. Gern, , Michael Inouye
The paper tracks the upper airway microbiome changes in preschool children and links them to asthma-associated persistent wheeze, showing that bacterial shifts precede viral infections and symptoms in sensitized children.
bioRxiv · Nov 20, 2017 · PreprintGenetics