Author

Hae-Won Shin

Washington University in St. LouisORCID 0000-0001-6316-8474Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:deconvolution· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alekhya ParvathaneniiD· 2 shared Junedh AmruteiD· 2 shared Kory J. LavineiD· 2 shared Ada Zhu· 1 shared Amal K. Dutta· 1 shared Ana VillanuevaiD· 1 shared Andrea L. BredemeyeriD· 1 shared Angeliki AsimakiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

Alekhya ParvathaneniORCID

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2 papers

Recent·Most cited

ImmunologyJACC Basic to Translational SciencePeer-reviewedMay 5, 2026

✦ In-depth digest

Interleukin-1β Drives Disease Progression in Arrhythmogenic Cardiomyopathy

Vinay R. Penna, Junedh Amrute, Morgan Engel…·Stephen P. Chelko

Human arrhythmogenic cardiomyopathy hearts harbor a lesion niche of POSTN fibroblasts and NLRP3+ inflammatory macrophages; IL-1β neutralization in Dsg2-mutant mice reduced fibrosis, dysfunction, and ventricular ectopy.

11 citationstop 1%

humanmouse

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ImmunologybioRxivPreprintJul 25, 2025

Targeting RUNX1 in Macrophages Facilitates Cardiac Recovery

Junedh Amrute, Ada Zhu, Yun-Ling Pai…·Kory J. Lavine

This study identifies RUNX1 as a key regulator of cardiac recovery by reprogramming macrophages, showing that its inhibition promotes heart function recovery in a chronic heart failure model.

2 citations

humanscRNA-seq

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