Author

Morgan Engel

Florida State UniversityORCID 0009-0009-4727-8070Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:deconvolution· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Emily A. ShieliD· 2 shared Stephen P. ChelkoiD· 2 shared Waleed Farra· 2 shared Alekhya ParvathaneniiD· 1 shared Ana VillanuevaiD· 1 shared Angeliki AsimakiiD· 1 shared Carlos Bueno‐BetíiD· 1 shared Christopher N. ToepferiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

Emily A. ShielORCID

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2 papers

Recent·Most cited

ImmunologyJACC Basic to Translational SciencePeer-reviewedMay 5, 2026

✦ In-depth digest

Interleukin-1β Drives Disease Progression in Arrhythmogenic Cardiomyopathy

Vinay R. Penna, Junedh Amrute, Morgan Engel…·Stephen P. Chelko

Human arrhythmogenic cardiomyopathy hearts harbor a lesion niche of POSTN fibroblasts and NLRP3+ inflammatory macrophages; IL-1β neutralization in Dsg2-mutant mice reduced fibrosis, dysfunction, and ventricular ectopy.

11 citationstop 1%

humanmouse

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BiophysicsbioRxivPreprintOct 3, 2025

Desmoglein-2 deficiency results in cardiac dysfunction by compromising both Z-disc- and intercalated disc-mediated mechanotransduction

Maicon Landim-Vieira, Vivek Jani, Emily Shiel…·Stephen P. Chelko

This study shows that DSG2 deficiency causes cardiac dysfunction by impairing Z-disc and intercalated disc mechanotransduction, leading to structural and functional cardiac defects.

DOI 10.1101/2025.10.03.680335

mouseproteomics

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