Author

Mario Mellado

Consejo Superior de Investigaciones CientíficasORCID 0000-0001-6325-1630Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Adriana Quijada‐FreireiD· 1 shared Blanca Soler PalaciosiD· 1 shared César A. SantiagoiD· 1 shared Enara San Sebastian· 1 shared Eva Armendariz-BurgoaiD· 1 shared Eva M. García‐CuestaiD· 1 shared Jakub ChojnackiiD· 1 shared Javier Martínez‐PicadoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Adriana Quijada‐FreireORCID

Mutual co-authors in cluster

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1 paper

Recent·Most cited

HIV-1 Envelope glycoprotein modulates CXCR4 clustering and dynamics on the T cell membrane

Adriana Quijada‐Freire, César A. Santiago, Eva M. García‐Cuesta, Blanca Soler Palacios, Rosa Ayala-Bueno, Sofía R. Gardeta, Enara San Sebastian, Eva Armendariz-Burgoa, Maria Carmen Puertas, Ricardo Villares, Urtzi Garaigorta, Luis Ignacio González‐Granado, José Miguel Rodrı́guez-Frade, Jakub Chojnacki, Javier Martínez‐Picado, Mario Mellado

This study shows that HIV-1 Env proteins induce CXCR4 clustering on T cells, which is linked to infection, and highlights the importance of co-receptor spatial organization in viral entry.

bioRxiv · Jun 11, 2025Immunology