Author

Jakub Chojnacki

IrsiCaixaORCID 0000-0002-4457-8096Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Javier Martínez‐PicadoiD· 2 shared Maria Carmen PuertasiD· 2 shared Adriana Quijada‐FreireiD· 1 shared Andrea Martí-SarriasiD· 1 shared Ángel Bayón-GiliD· 1 shared Blanca Soler PalaciosiD· 1 shared César A. SantiagoiD· 1 shared Christian EggelingiD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

Javier Martínez‐PicadoORCID

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Author profile →

3 papers

Recent·Most cited

MIF overexpression upon SARS-CoV-2 infection induces neural regeneration in human-derived brain organoids

Andrea Martí-Sarrias, Maria Carmen Puertas, Isabel Turpín, Lidia Garrido-Sanz, Ángel Bayón-Gil, Patricia Resa‐Infante, Jakub Chojnacki, Maria C. García-Guerrero, Víctor Urrea, Ramón Lorenzo-Redondo, Sandra Acosta, Javier Martínez‐Picado

This study shows that MIF overexpression after SARS-CoV-2 infection promotes neural regeneration in human brain organoids through EGFR signaling and self-upregulation.

bioRxiv · Feb 16, 2026 · PreprintCell Biology

HIV-1 Envelope glycoprotein modulates CXCR4 clustering and dynamics on the T cell membrane

Adriana Quijada‐Freire, César A. Santiago, Eva M. García‐Cuesta, Blanca Soler Palacios, Rosa Ayala-Bueno, Sofía R. Gardeta, Enara San Sebastian, Eva Armendariz-Burgoa, Maria Carmen Puertas, Ricardo Villares, Urtzi Garaigorta, Luis Ignacio González‐Granado, José Miguel Rodrı́guez-Frade, Jakub Chojnacki, Javier Martínez‐Picado, Mario Mellado

This study shows that HIV-1 Env proteins induce CXCR4 clustering on T cells, which is linked to infection, and highlights the importance of co-receptor spatial organization in viral entry.

bioRxiv · Jun 11, 2025Immunology

Advanced processing and analysis of conventional confocal microscopy generated scanning FCS data

Dominic Waithe, Falk Schneider, Jakub Chojnacki, Mathias Clausen, Dilip Shrestha, Jorge Bernardino de la Serna, Christian Eggeling

This paper optimizes processing and analysis of scanning FCS data, introducing FoCuS-scan software and addressing bias and variance in diffusion measurements.

bioRxiv · Jul 31, 2017 · PreprintBiophysics