Developmental BiologyStem Cell ReportsPeer-reviewed
Human pluripotent stem cell-derived kidney organoids reveal tubular epithelial pathobiology of heterozygous HNF1B-associated dysplastic kidney malformations
Ioannis Bantounas, Kirsty M. Rooney, Filipa M. Lopes…·Susan J. Kimber
This study uses HNF1B mutant kidney organoids to reveal molecular and physiological defects in dysplastic kidney malformations and identify potential therapeutic targets.