Filipa M. Lopes

This study shows that adding human pluripotent stem cell-derived macrophages to kidney organoids affects their development, increasing glomeruli area but also causing growth inhibition and dysmorphic tissue when added in high numbers.

This paper demonstrates that AAV-mediated HPSE2 gene transfer improves bladder function in a mouse model of urofacial syndrome by restoring neurogenic relaxation.

This study uses HNF1B mutant kidney organoids to reveal molecular and physiological defects in dysplastic kidney malformations and identify potential therapeutic targets.