Martin Wegner

The paper investigates how centrosome architecture and m6A-dependent regulation influence p53 surveillance after whole-genome doubling, identifying key molecular mechanisms.

ReCo automates the generation of read-count tables for CRISPR gRNAs from NGS data, enabling downstream analysis of gRNA-induced phenotypes.

This paper introduces a new method to identify gene-specific regulatory elements by integrating epigenomics data and demonstrates its application in prioritizing doxorubicin-resistance genes.

The paper introduces a computational pipeline to interpret CRISPR mutations in non-coding regions using epigenomic data, revealing novel regulatory elements involved in chemoresistance.